UNLV defeated Wyoming 31-17 on Saturday in Week 6 action. The Rebels controlled the game from the opening drive, scoring 17 points in the first quarter alone behind a Keyvone Lee touchdown run. UNLV extended its lead to 24-3 by halftime before Wyoming mounted a second-half comeback.

The Cowboys scored touchdowns in both the third and fourth quarters to make it competitive, with Deion DeBlanc scoring on the ground in the third quarter. However, UNLV sealed the victory with a fourth-quarter touchdown pass from Anthony Colandrea to Jai'Den Thomas.

UNLV's defense was instrumental early, forcing a crucial fumble recovery by Mumu Bin-Wahad in the second quarter that stalled a Wyoming drive. Jai'Den Thomas led all rushers with 96 yards for the Rebels, while Wyoming's Kaden Anderson completed 254 passing yards and Eric Richardson caught 9 passes in the loss.

UNLV covered the 4-point spread as the away team, while the game finished under the 51-point over-under total.